Thionyl Chloride → 2-bromo-4,5,6,7-tetrahydro-N-(4-fluoro-2-hydroxyphenyl)-benzo[b]thiophene-3-carboxamide

HRID 203730Notes

Reaction equation

HRID 203730 reaction equation
[Br:1][c:2]1[c:3]([C:11](=[O:12])[OH:13])[c:4]2[c:5]([s:6]1)[CH2:7][CH2:8][CH2:9][CH2:10]2.[NH2:18][c:19]1[c:20]([OH:26])[cH:21][c:22]([F:25])[cH:23][cH:24]1.[S:14]([Cl:15])([Cl:16])=[O:17]>>[Br:1][c:2]1[c:3]([C:11](=[O:13])[NH:18][c:19]2[c:20]([OH:26])[cH:21][c:22]([F:25])[cH:23][cH:24]2)[c:4]2[c:5]([s:6]1)[CH2:7][CH2:8][CH2:9][CH2:10]2

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 1857632-Amino-5-fluorophenolHCID 184221372-Bromo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

Product 1

HCID 184222552-bromo-4,5,6,7-tetrahydro-N-(4-fluoro-2-hydroxyphenyl)-benzo[b]thiophene-3-carboxamide

Sources & evidence

ORD record
ord-22d234c595954111b0656cbc27897495
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…