HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-4-hydroxy-5-methoxybenzaldehyde → 3-Chloro-4-hydroxy-5-methoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-4-hydroxy-5-methoxybenzaldehyde | HCID 29622 | — |
| Reactant | 3-Ethyl-4-hydroxy-5-methylbenzonitrile | HCID 59759950 | — |
| Product | 3-Chloro-4-hydroxy-5-methoxybenzonitrile | HCID 1220717 | — |
Reaction Steps
The title compound is prepared from commercially available 3-chloro-4-hydroxy-5-methoxy-benzaldehyde in analogy to literature procedures (see 3-ethyl-4-hydroxy-5-methyl-benzonitrile); LC-MS: tR=0.82 min; 1H NMR (CDCl3): δ3.98 (s, 3H), 6.36 (s, 1H), 7.04 (s, 1H), 7.34 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575200B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-33130bd850b34751a37878d458263873 |
| Source note | uspto-grants-2013_11 |