2-Fluoroethylamine → HCID 58109313, compound

Participants

Reaction Steps

The title compound was prepared from (S)-3-((S)-1-(4-bromophenyl)ethyl)-6-(4-fluorophenyl)-6-(2-hydroxyethyl)-1,3-oxazinan-2-one and 2-fluoroethylamine following procedures analogous to those described in Example 178. LC-MS Method 2 tR=1.1 min, m/z=489; 1H NMR (CDCl3) 1.50 (d, 3H), 1.97-2.38 (m, 7H), 2.41-2.56 (m, 1H), 2.79-2.98 (m, 3H), 4.45 (m, 1H), 4.54 (m, 1H), 5.61 (m, 1H), 6.80 (d, 2H), 7.03-7.14 (t, 2H), 7.21-7.31 (m, 6H).

Provenance & Evidence