(6-Aminopyridin-3-yl)boronic acid → HCID 59532371, compound

Participants

Reaction Steps

The title compound was prepared from (R)-3-((S)-1-(4-bromophenyl)ethyl)-6-(3-hydroxypropyl)-6-phenyl-1,3-oxazinan-2-one and 6-aminopyridine-3-boronic acid following procedures analogous to those described in Example 75 Step 1. LC-MS Method 2 tR=0.963 min, m/z=431.8; 1H NMR (CDCl3) 1.36 (d, 3H), 1.75 (m, 1H), 1.98 (m, 3H), 2.21 (m, 1H), 2.38 (m, 2H), 2.89 (m, 1H), 3.56 (m, 2H), 5.05 (s, 1H), 5.65 (m, 1H), 6.62 (d, 1H), 6.97 (d, 2H), 7.17 (d, 2H), 7.20-7.39 (m, 5H), 7.63 (d, 1H), 8.12 (s, 1H).

Provenance & Evidence