2-Methylpyridine-4-boronic acid → HCID 58109337, compound

Participants

Reaction Steps

The title compound was prepared from N-(3-((R)-3-((S)-1-(4-bromophenyl)ethyl)-2-oxo-6-phenyl-1,3-oxazinan-6-yl)propyl)methanesulfonamide and 2-methylpyridine-4-boronic acid following procedures analogous to those described in Example 75 Step 1. LC-MS Method 2 tR=0.988 min, m/z=508.2; 1H NMR (CDCl3) 1.36 (m, 1H), 1.51 (d, 3H), 1.70 (m, 1H), 1.96 (m, 2H), 2.17 (m, 1H), 2.26 (m, 2H), 2.59 (s, 3H), 2.86 (m, 4H), 3.02 (m, 2H), 4.19 (m, 1H), 5.62 (m, 1H), 6.96 (d, 2H), 7.19 (m, 3H), 7.26 (d, 2H), 7.29 (m, 4H), 8.47 (d, 1H).

Provenance & Evidence