Pivalic acid → HCID 58109415, compound

Participants

Reaction Steps

The title compound was prepared (S)-6-(2-amino-2-methylpropyl)-3-((S)-1-(4-bromophenyl)ethyl)-6-phenyl-1,3-oxazinan-2-one following a procedure analogous to that described in Example 688 using pivalic acid. LC-MS Method 1 tR=2.05 min, m/z=515; 1H NMR (CDCl3) 7.36-7.27 (5H, m), 7.22 (2H, d, J=8.5 Hz), 6.79 (2H, d, J=8.2 Hz), 6.20 (1H, s), 5.58 (1H, q, J=7.0 Hz), 2.79 (1H, m), 2.44 (1H, d, J=15.5 Hz), 2.37 (1H, d, J=15.2 Hz), 2.24-2.06 (3H, m), 1.47 (3H, d, J=7.03 Hz), 1.37 (3H, s) 1.10 (9H, s), 1.05 (3H, s).

Provenance & Evidence