反应详情

3 g of 2-(1-imidazolylcarbonylamino)-6-methyl-4[1H]-pyrimidinone (136 mmol) prepared according to the procedure described by Meijer et al., J. Am. Chem. Soc. 2003, 125, p. 6860 are added to a solution of 0.81 g of N-methyldiaminoethylamine (6.8 mmol) in 150 ml of dichloromethane. The solution is stirred at reflux for 4.5 hours. The product is precipitated from acetone, filtered off and washed with acetone, and then dried under reduced pressure.

1. temperatureat reflux for 4.5 hours
2. customThe product is precipitated from acetone
3. filtrationfiltered off
4. washwashed with acetone
5. customdried under reduced pressure