HRID2038172

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCOc1nc(N)c2nc(OC)n(CCCC3CCCCN3C(=O)OCc3ccccc3)c2n1

HCID58306132

未命名化合物

HCID58306246

未命名化合物

2 次

结构：CCCCOc1nc(N)c2nc(OC)[nH]c2n1.O=C(O)C(F)(F)F

HCID178450370

未命名化合物

2 次

PRODUCTS

生成物

结构：CCCCOc1nc(N)c2nc(OC)n(CCCCC3CCCN(C(=O)OCc4ccccc4)C3)c2n1

HCID58306189

未命名化合物

PROCEDURE

实验过程

Prepared similarly to Intermediate 11 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate (for example, as prepared for Intermediate 6) and phenylmethyl 3-(4-bromobutyl)-1-piperidinecarboxylate (for example, as prepared for Intermediate 24).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2c3942ef89c2404da684e385be5cc98c
来源数据集: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08575340B2
来源说明: uspto-grants-2013_11

反应 SMILES

[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([O:35][CH3:36])[N:6]2[CH2:16][CH2:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:25]([O:27][CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)=[O:26].F[C:38](F)(F)C(O)=O.C(OC1N=C2C(N=C(OC)N2)=C(N)N=1)CCC.BrCCCCC1CCCN(C(OCC2C=CC=CC=2)=O)C1>>[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([O:35][CH3:36])[N:6]2[CH2:16][CH2:17][CH2:18][CH2:19][CH:24]1[CH2:23][CH2:22][CH2:21][N:20]([C:25]([O:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)=[O:26])[CH2:38]1