Benzene, (2-bromoethoxy)- → HCID 11705919, compound

HRID 2038231Notes

Reaction equation

HRID 2038231 reaction equation
[N:1]12[CH2:8][CH2:7][C:4]([C:9]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[OH:10])([CH2:5][CH2:6]1)[CH2:3][CH2:2]2.[C:23]1([O:29][CH2:30][CH2:31][Br:32])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>CC#N>[Br-:32].[OH:10][C:9]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)([C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)[C:4]12[CH2:5][CH2:6][N+:1]([CH2:31][CH2:30][O:29][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)([CH2:2][CH2:3]1)[CH2:8][CH2:7]2

Participants

4

Reactant 2

HCID 68526Benzene, (2-bromoethoxy)-HCID 239923851-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol

Product 1

HCID 11705919HCID 11705919, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a solution of 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0550 g, 0.187 mmol) in 2 CH3CN/3CHCl3 (2.5 mL) was added 2-bromoethyl phenyl ether (0.060 g, 0.29 mmol).

Sources & evidence

ORD record
ord-670f62ffd30d4032a38cd9cf22f72c1d
Source dataset
uspto-grants-2013_11
Patent number
US08575347B2

Reaction notes

Loading…