HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Bromide → HCID 42625933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Bromide | HCID 6323 | — |
| Reactant | Butyl methyl ether | HCID 12338 | — |
| Reactant | 1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol | HCID 23992385 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 42625933 | HCID 42625933 | 88% |
Reaction Steps
Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct -4-yl(diphenyl)methanol (0.0638 g, 0.217 mmol) and bromomethane (2.0 M in t -Butylmethyl ether, 0.250 mL, 0.500 mmol) in 2 CH3CN/3CHCl3 (4.0 mL) were reacted to give the desired product (0.0739 g, 88.0%). ELMS m/z 308(M+) Rt (1.58 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575347B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-b8a48b58cab447cbbe54e3e0903b3daa |
| Source note | uspto-grants-2013_11 |