Benzene, (2-bromoethoxy)- → 4-[Hydroxy(di-2-thienyl)methyl]-1-[2-(phenyloxy)ethyl]-1-azoniabicyclo[2.2.2]octane bromide

Participants

Reaction Steps

Following the general procedure outlined in Example 4, 1-azabicyclo[2.2.2]oct -4-yl(di-2-thienyl)methanol (0.0693 g, 0.227 mmol) and 2-bromoethyl phenyl ether (0.056 g, 0.279 mmol) in 1MeOH/1CHCl3 (3.0 mL) were reacted to give the desired product (0.0822 g, 74.7%). ELMS m/z 426(M+) Rt (2.00 min).

Provenance & Evidence