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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2038361Generated: November 2, 2026

2-Bromo-3'-chloroacetophenone → Ethyl 4-(3-chlorophenyl)-1,3-thiazole-2-carboxylate

https://huagongshe.com/reaction/2038361

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-3'-chloroacetophenoneHCID 38738—
ReactantEthyl 4-(3-chloro-4-fluorophenyl)-1,3-thiazole-2-carboxylateHCID 61385370—
ProductEthyl 4-(3-chlorophenyl)-1,3-thiazole-2-carboxylateHCID 10264991—

Reaction Steps

The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 2A starting with 2-bromo-1-(3-chlorophenyl)ethanone. 1.51 g (73% of theory) of the title compound are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575357B2
Source datasetuspto-grants-2013_11
ORD IDord-ddb37b4bcaf54bbba78b2b58e6fe139a
Source noteuspto-grants-2013_11