HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(3-chlorophenyl)-1,3-thiazole-2-carboxylate → Ethyl 5-bromo-4-(3-chlorophenyl)-1,3-thiazole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(3-chlorophenyl)-1,3-thiazole-2-carboxylate | HCID 10264991 | — |
| Reactant | Ethyl 5-bromo-4-(3-chloro-4-fluorophenyl)-1,3-thiazole-2-carboxylate | HCID 70801639 | — |
| Product | Ethyl 5-bromo-4-(3-chlorophenyl)-1,3-thiazole-2-carboxylate | HCID 70801641 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 4A starting with the compound of Example 3A. 1.95 g of the title compound having a purity of 65% (98% of theory) are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575357B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-870d26214e084fd683defdd0971ace5a |
| Source note | uspto-grants-2013_11 |