Boron trifluoride → HCID 59625898, compound

Participants

Reaction Steps

Methyl 4-benzoylbenzoate 18a (0.50 g, 2.08 mmol) and BF3.(OAc)2 (0.73 mL, 5.2 mmol) were dissolved in dry CH2Cl2 under a N2 atmosphere. Ethane-1,2-dithiol (0.333 mL, 3.95 mmol) was added and the solution was stirred overnight. The reaction mixture was partitioned between CH2Cl2 and water. The organic layer was concentrated and purified by flash column chromatography (silica gel, 10% EtOAc/hexanes) to afford compound 18b.

Provenance & Evidence