HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-Methyl 1-((tert-butoxycarbonyl)amino)-2-vinylcyclopropanecarboxylate → (1r,2s)-1-Amino-2-vinylcyclopropane carboxylic acid methyl ester trifluoroacetic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-Methyl 1-((tert-butoxycarbonyl)amino)-2-vinylcyclopropanecarboxylate | HCID 10421813 | — |
| Reactant | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | (1r,2s)-1-Amino-2-vinylcyclopropane carboxylic acid methyl ester trifluoroacetic acid salt | HCID 67246036 | — |
Reaction Steps
N-Boc-(1R,2S)-1-amino-2-vinylcyclopropane carboxylic acid methyl ester (125 mg, 0.52 mmol) stirred in CH2Cl2/TFA (1:1, 2 mL) at RT for 90 minutes. Solvents removed under vacuum to yield (1R,2S)-1-amino-2-vinylcyclopropane carboxylic acid methyl ester trifluoroacetic acid salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575208B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-06a7fd40de974ea38e913c2e1ec810d2 |
| Source note | uspto-grants-2013_11 |