4-Methyl-1,3-oxazolidin-2-one → 6-[4-[2-Fluoro-4-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzoyl]piperazin-1-yl]-5-methylpyridine-3-carbonitrile

HRID 203884Notes

Reaction equation

HRID 203884 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:25])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][c:21]3[CH3:22])[CH2:12][CH2:13]2)[cH:23][cH:24]1.[CH3:26][CH:27]1[NH:28][C:29](=[O:32])[O:30][CH2:31]1>>[c:2]1([N:28]2[CH:27]([CH3:26])[CH2:31][O:30][C:29]2=[O:32])[cH:3][c:4]([F:25])[c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][cH:16][c:17]([C:18]#[N:19])[cH:20][c:21]3[CH3:22])[CH2:12][CH2:13]2)[cH:23][cH:24]1

Participants

3

Reactant 2

HCID 98554554-Methyl-1,3-oxazolidin-2-oneHCID 584846066-[4-(4-Bromo-2-fluorobenzoyl)piperazin-1-yl]-5-methylnicotinonitrile

Product 1

HCID 673812726-[4-[2-Fluoro-4-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzoyl]piperazin-1-yl]-5-methylpyridine-3-carbonitrile

Sources & evidence

ORD record
ord-e27275f3a79b474d910329c39b7e553d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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