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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2039004Generated: November 1, 2026

2-(3-Methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acid ethyl ester → 2-(3-Methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acid

https://huagongshe.com/reaction/2039004

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acid ethyl esterHCID 66620164—
Reactant4-Oxo-hexahydro-pyrrolo[1,2-a]pyrazine-2,6-dicarboxylic acid 6-ethyl ester 2-methyl esterHCID 66620549—
Product2-(3-Methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acidHCID 66621069—

Reaction Steps

2-(3-Methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acid was prepared by method 801 substituting 2-(3-methoxycarbonylamino-2-oxo-piperidin-1-yl)-propionic acid ethyl ester for 4-oxo-hexahydro-pyrrolo[1,2-a]pyrazine-2,6-dicarboxylic acid 6-ethyl ester 2-methyl ester. C10H16N2O5 calculated 244.1 observed [M+1]+ 245.1; rt=1.53 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575118B2
Source datasetuspto-grants-2013_11
ORD IDord-b952fc0b2f8a4174a0aa5f28cf0e053e
Source noteuspto-grants-2013_11