Acetic Acid → Methyl 2-isopropylhydrazinecarboxylate

HRID 2039164Notes

Reaction equation

HRID 2039164 reaction equation
[CH3:1][O:2][C:3]([NH:5][N:6]=[C:7]([CH3:9])[CH3:8])=[O:4].C(O)(=O)C>C(O)C>[CH3:1][O:2][C:3]([NH:5][NH:6][CH:7]([CH3:9])[CH3:8])=[O:4]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 9095211-Methoxycarbonyl-2-isopropylidene hydrazine

Product 1

HCID 57863323Methyl 2-isopropylhydrazinecarboxylateYield 77.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N′-Isopropylidene-hydrazine-carboxylic acid methyl ester (6.45 g) were dissolved in ethanol (50 mL) and acetic acid (50 mL) PtO2 (0.231 g) was added, and reaction was stirred at room temperature for 22 hours under an atmosphere of hydrogen. Mixture was evaporated under vacuum, giving N′-Isopropyl-hydrazine-carboxylic acid methyl ester (5.08 g, 77%) as a white solid.

Workup

  1. customreaction
  2. customMixture was evaporated under vacuum

Sources & evidence

ORD record
ord-8086ce8bff854737b4c9acabcdb2b343
Source dataset
uspto-grants-2013_11
Patent number
US08575118B2

Reaction notes

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