HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fexofenadine Hydrochloride → Fexofenadine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fexofenadine Hydrochloride | HCID 63002 | — |
| Reactant | HCID 178435160 | HCID 178435160 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | Fexofenadine | HCID 3348 | — |
Reaction Steps
Cyclohexane is poured into the microencapsulation reactor. Then, under continuous stirring, fexofenadine HCl, ethylcellulose (EC) and polyethylene are added. The mixture is heated and then cooled down. Microcapsules are recovered, and then washed (one or more times), filtered, and dried over night (about 16 h) in a fume hood or in a hood at 40° C. The powder is sieved through a 300 μm opening sieve.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580313B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-2e5d212221434624981b00b584e26e76 |
| Source note | uspto-grants-2013_11 |