HCID 67042920, compound → HCID 69927716, compound

HRID 2039528Notes

Reaction equation

HRID 2039528 reaction equation
C[O:2][C:3]1[CH:26]=[C:25]([O:27]C)[CH:24]=[CH:23][C:4]=1[CH2:5][C:6]1[N:15]2[N:16]=[C:17]([NH2:19])[N:18]=[C:14]2[C:13]2[CH:12]=[CH:11][C:10]([N+]([O-])=O)=[CH:9][C:8]=2[N:7]=1.COC1C=C(C=C(OC)C=1)CC1N2N=C(N)N=C2C2C=CC=CC=2N=1>>[NH2:19][C:17]1[N:18]=[C:14]2[N:15]([C:6]([CH2:5][C:4]3[CH:23]=[CH:24][C:25]([OH:27])=[CH:26][C:3]=3[OH:2])=[N:7][C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=32)[N:16]=1

Participants

3

Reactant 2

HCID 67042920HCID 67042920, compoundHCID 67042932HCID 67042932, compound

Product 1

HCID 69927716HCID 69927716, compoundYield 76%

Procedure

Operating as in Example 39, but employing 5-(2,4-dimethoxy-benzyl)-8-nitro-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, prepared as described in Example 5, instead of 5-(3,5-dimethoxy-benzyl)-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, the title compound was obtained in 76% yield.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-1a19d0fd9b17414b86a53f53739576f6
Source dataset
uspto-grants-2013_11
Patent number
US08580783B2

Reaction notes

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