HCID 67042612, compound → HCID 69927546, compound

HRID 2039529Notes

Reaction equation

HRID 2039529 reaction equation
C[O:2][C:3]1[CH:23]=[CH:22][C:6]([CH2:7][C:8]2[N:17]3[N:18]=[C:19]([NH2:21])[N:20]=[C:16]3[C:15]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:5][CH:4]=1.COC1C=C(C=C(OC)C=1)CC1N2N=C(N)N=C2C2C=CC=CC=2N=1>>[NH2:21][C:19]1[N:20]=[C:16]2[N:17]([C:8]([CH2:7][C:6]3[CH:5]=[CH:4][C:3]([OH:2])=[CH:23][CH:22]=3)=[N:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=32)[N:18]=1

Participants

3

Reactant 2

HCID 67042612HCID 67042612, compoundHCID 67042932HCID 67042932, compound

Product 1

HCID 69927546HCID 69927546, compoundYield 71%

Procedure

Operating as in Example 39, but employing 5-(4-methoxy-benzyl)-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, prepared as described in Example 3, instead of 5-(3,5-dimethoxy-benzyl)-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, the title compound was obtained in 71% yield.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-0b5c76bee1ff4fc8b6f8e5ceebcee48f
Source dataset
uspto-grants-2013_11
Patent number
US08580783B2

Reaction notes

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