HCID 67042932, compound → HCID 69927281, compound

HRID 2039531Notes

Reaction equation

HRID 2039531 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([CH:21]=[CH:22][C:23]=1[O:24]C)[CH2:6][C:7]1[N:16]2[N:17]=[C:18]([NH2:20])[N:19]=[C:15]2[C:14]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N:8]=1.COC1C=C(C=C(OC)C=1)CC1N2N=C(N)N=C2C2C=CC=CC=2N=1>>[NH2:20][C:18]1[N:19]=[C:15]2[N:16]([C:7]([CH2:6][C:5]3[CH:4]=[C:3]([OH:2])[C:23]([OH:24])=[CH:22][CH:21]=3)=[N:8][C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=32)[N:17]=1

Participants

3

Reactant 2

HCID 67042932HCID 67042932, compoundHCID 67043239HCID 67043239, compound

Product 1

HCID 69927281HCID 69927281, compoundYield 37%

Procedure

Operating as in Example 39, but employing 5-(3,4-dimethoxy-benzyl)-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, prepared as described in Example 7, instead of 5-(3,5-dimethoxy-benzyl)-[1,2,4]triazolo[1,5-c]quinazolin-2-ylamine, the title compound was obtained in 37% yield.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-a62d48dab255471cbc78e17f65c8de3d
Source dataset
uspto-grants-2013_11
Patent number
US08580783B2

Reaction notes

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