tert-Butanol → HCID 57855964, compound

Participants

Reaction Conditions

Reaction Steps

7.1 g (30.6 mmol) quinoxaline-6,7-dicarboxylic acid monomethyl ester, 8 ml NEt3, 1 g molecular sieve 4 Å and 10 ml (46.40 mmol) diphenylphosphonic azide is successively added to 100 ml t-butanol. The mixture is heated at a temperature of 85° C. during 20 hours. After cooling, the mixture is filtered and the solid is washed with 1000 ml THF. The filtrate is evaporated and submitted to flash-chromatography to give 7.45 g (80%) of the title compound. m.p.: 196-198° C.

Provenance & Evidence