Cyclopropanemethanamine → HCID 57855955, compound

Participants

Reaction Steps

See step f) of example H2 using 4-chloro-6-[2-(3-chloro-pyridin-2-yl)-5-trifluoromethyl-2H-pyrazol-3-yl]-2-methoxy-3a,9a-dihydro-7-oxa-3-thia-1,5-diaza-cyclopenta[b]naphthalen-8-one as starting material and cyclopropanemethylamine. After overnight reaction and chromatography column purification, the expected product is obtained within 34%; LC/MS: 585/587 (M+1)+; m.p.: 199-201° C.

Provenance & Evidence