HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Disulfide → HCID 178497011, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Disulfide | HCID 6348 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 57855980 | HCID 57855980 | — |
| Reactant | HCID 57855982 | HCID 57855982 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178497011 | HCID 178497011 | — |
Reaction Steps
This compound is synthesized as reported in U.S. Pat. No. 4,454,148. 2,5-Diamino-3-chloro-4-(2-trimethylsilanyl-ethylsulfanyl)-benzoic acid methyl ester (step d in example H17) is used as starting material and after thiol deprotection (step f in example H17), the crude 2,5-diamino-3-chloro-4-mercapto-benzoic acid methyl ester is cyclized with CS2, NaOH in EtOH at 70° C. The crude is directly used in the next step without further purification; LC/MS: 275/277 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580785B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-95172c9ce7c54b4c86771240c98cfc0c |
| Source note | uspto-grants-2013_11 |