HCID 57855965, compound → HCID 57855894, compound

Participants

Reaction Steps

A solution of 5-Methyl-6-nitro-2-trifluoromethyl-quinoline-7-carboxylic acid (1.40 g, 4.66 mmol) in ethanol (100 ml) is hydrogenated at atmospheric pressure and ambient temperature in the presence of Raney-nickel catalyst. TLC analysis after 12 hr shows reaction completion. The mixture is filtered over hyflo and the filtrate concentrated in vacuo. The residue is recrystallised from hexane/ethyl acetate to give 0.9 g (71%) of the title compound as yellow crystals.

Provenance & Evidence