HCID 57855910, compound → HCID 57855900, compound

HRID 2039646Notes

Reaction equation

HRID 2039646 reaction equation
[CH3:1][O:2][C:3]1[C:12]([N+:13]([O-])=O)=[C:11]([C:16]([OH:18])=[O:17])[CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([C:19]([F:22])([F:21])[F:20])=[N:8]2>C(O)C.[Ni]>[NH2:13][C:12]1[C:3]([O:2][CH3:1])=[C:4]2[C:9](=[CH:10][C:11]=1[C:16]([OH:18])=[O:17])[N:8]=[C:7]([C:19]([F:20])([F:21])[F:22])[CH:6]=[CH:5]2

Participants

4

Reactant 1

HCID 57855910HCID 57855910, compound

Product 1

HCID 57855900HCID 57855900, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

A sample of 5-Methoxy-6-nitro-2-trifluoromethyl-quinoline-7-carboxylic acid is hydrogenated in ethanol in the presence of Raney-Ni analogously to the procedure described for example H-18, step g). This gives the title product as yellow crystals.

Sources & evidence

ORD record
ord-183f3605603340248f422792f16c53d8
Source dataset
uspto-grants-2013_11
Patent number
US08580785B2

Reaction notes

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