HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 68314109, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-Benzylethylenediamine | HCID 77801 | — |
| Reactant | Methyl 6-chloropyridine-3-carboxylate | HCID 254249 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68314109 | HCID 68314109 | — |
Reaction Steps
4.6 g of methyl 6-chloronicotinate and 40.5 ml of N-benzylethylenediamine are heated at 135° C. for 6 hours in a round-bottomed flask. The resulting product is poured into water and extraction is carried out with ethyl acetate. The resulting product is dried and evaporated under vacuum; the crude product thus obtained is purified by flash chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580790B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-54e0bce5d4554762b994927b3f6ca088 |
| Source note | uspto-grants-2013_11 |