6-phenylpyrimidin-4-amine → HCID 23633266, compound

Participants

Reaction Steps

The title compound was prepared in the same manner as described for 4-{-4-[3-(6-tert-butylpyrimidin-4-yl)ureido]phenoxy}pyridine-2-carbothioic acid amide, replacing 6-amino-4-tert-butylpyrimidine for 6-amino-4-phenylpyrimidine. 1H-NMR (DMSO-d6) δ 10.18 (broad s, 1H), 10.04 (broad s, 1H), 9.91 (broad s, 1H), 9.85 (broad s, 1H), 8.78 (d, J=1.2 Hz, 1H), 8.45 (d, J=5.7 Hz, 1H), 8.15 (s, 1H), 8.06 to 8.02 (m, 2H), 7.94 (d, J=2.7 Hz, 1H), 7.64 (d, J=8.7 Hz, 2H), 7.54 to 7.52 (m, 3H), 7.20 (d, J=8.7 Hz, 2H), 7.12 (dd, J=5.7, 3.0 Hz, 1H); LC-MS m/z 443 [M+H]+, RT=3.19 min.

Provenance & Evidence