Diethyl Malonate → HCID 6999756, compound

Participants

Reaction Steps

trans-β-Nitrostyrene (34.3 mg, 0.23 mmol), diethyl malonate (0.065 mL, 0.46 mmol) and the compound (10 mol %) shown in the following Table 1 as an asymmetric catalyst were stirred in toluene (0.4 mL) at room temperature. The reaction mixture was purified by silica gel column chromatography (n-hexane/ethyl acetate=95/5→90/10→80/20) to give the title compound.

Provenance & Evidence