Benzamide → HCID 67250615, compound

Participants

Reaction Steps

2-Acetamido-N-(3-((5-benzoyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-5-chlorophenyl)acetamide was synthesized using 2-acetamidoacetic acid and (4-((3-amino-5-chlorophenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)(phenyl)methanone according to the procedure for the synthesis of N-3-((5-benzoyl-7H-pyrrolo[2,3-d]pyridine-4-yl)amino)phenyl)benzamide. A white solid was obtained. M.p.>300° C.; 400 MHz 1HNMR (DMSO-d6) δ 11.53 (s, 1H), 10.24 (s, 1H), 8.53 (s, 1H), 8.25-8.22 (m, 1H), 8.11-8.10 (m, 1H), 8.00 (d, J=2.0 Hz, 1H), 7.87 (s, 1H), 7.86-7.85 (m, 1H), 7.81-7.81 (m, 1H), 7.69-7.67 (m, 1H), 7.61-7.57 (m, 2H), 7.51-7.50 (m, 1H), 3.87 (d, J=6.0 Hz, 2H), 1.90 (s, 3H); LCMS [M+H] 463.

Provenance & Evidence