HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-bromopropanoate → 2-{4-[5-(2-Fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenoxy}propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-bromopropanoate | HCID 545327 | — |
| Reactant | HCID 71186361 | HCID 71186361 | — |
| Reactant | 4-[5-(2-Fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenol | HCID 136413238 | — |
| Product | 2-{4-[5-(2-Fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenoxy}propionic acid | HCID 71186016 | — |
Reaction Steps
2-{4-[5-(2-Fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenoxy}propionic acid was prepared analogously to Example 1 (steps (e) and (f)) by reaction of 4-[5-(2-fluorophenoxy)oxazolo[5,4-b]pyridin-2-yl]-2,6-dimethylphenol with tert-butyl 2-bromopropionate and subsequent ester cleavage.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580816B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-ee80ca5016bd4a70892e8d470c79b286 |
| Source note | uspto-grants-2013_11 |