Benzyl Bromide → HCID 86615506, compound

Participants

Reaction Steps

To a solution of 3-(3,5-bis-trifluoromethyl-benzyloxymethyl)-4-o-tolyl-pyridine (prepared as described in DE 10008042 A1; 150 mg, 0.353 mmol) and benzyl bromide (60 mg, 0.35 mmol) in 3 ml acetonitrile was heated at reflux for 5 h. The mixture was concentrated in vacuo and the residue was purified by flash column chromatography to give 163 mg (78%) of the title compound as a white solid.

Provenance & Evidence