5-Fluoro-2-methylphenol → HCID 66922132, compound

HRID 2039822Notes

Reaction equation

HRID 2039822 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:20]3[CH:21]=[N:22][CH:23]=[CH:24][C:19]=3[N:18]([C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)[C:17]=2Cl)=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:33][C:34]1[CH:35]=[CH:36][C:37]([CH3:41])=[C:38]([OH:40])[CH:39]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:20]3[CH:21]=[N:22][CH:23]=[CH:24][C:19]=3[N:18]([C:25]3[CH:30]=[CH:29][C:28]([F:31])=[CH:27][CH:26]=3)[C:17]=2[O:40][C:38]2[CH:39]=[C:34]([F:33])[CH:35]=[CH:36][C:37]=2[CH3:41])=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27746165-Fluoro-2-methylphenolHCID 66922199HCID 66922199, compound

Product 1

HCID 66922132HCID 66922132, compound

Procedure

The crude title compound was prepared from the compound of step 5 (50.0 mg, 109 μmol) and 5-fluoro-2-methylphenol analogously as described in example 1, step 6.

Sources & evidence

ORD record
ord-cf3653715f344ff78ea380f8ad4de11f
Source dataset
uspto-grants-2013_11
Patent number
US08580813B2

Reaction notes

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