5-Fluoro-2-methylphenol → HCID 66922373, compound

HRID 2039828Notes

Reaction equation

HRID 2039828 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][N:21]=[C:22]([O:25][CH3:26])[CH:23]=3)[N:18]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:17]=2Cl)=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:34][C:35]1[CH:36]=[CH:37][C:38]([CH3:42])=[C:39]([OH:41])[CH:40]=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][N:21]=[C:22]([O:25][CH3:26])[CH:23]=3)[N:18]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:17]=2[O:41][C:39]2[CH:40]=[C:35]([F:34])[CH:36]=[CH:37][C:38]=2[CH3:42])=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 27746165-Fluoro-2-methylphenolHCID 66922363HCID 66922363, compound

Product 1

HCID 66922373HCID 66922373, compound

Procedure

The title compound was prepared from the compound of step 5 (100 mg, 212 μmol) and 5-fluoro-2-methylphenol analogously as described in example 1, step 6. Yield: 98.0 mg.

Sources & evidence

ORD record
ord-ce5bfeb0d25b4f798872dfd2b4322f0d
Source dataset
uspto-grants-2013_11
Patent number
US08580813B2

Reaction notes

Loading…