HRID2039870

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11335

2,6-Dimethylphenol

C8H10O

结构：COC(=O)CC1CN(C(=O)c2c(Cl)n(-c3ccccc3)c3cccnc23)CCN1C(=O)OC(C)(C)C

HCID66922233

未命名化合物

PRODUCTS

生成物

结构：COC(=O)CC1CN(C(=O)c2c(Oc3c(C)cccc3C)n(-c3ccccc3)c3cccnc23)CCN1C(=O)OC(C)(C)C

HCID66922257

未命名化合物

PROCEDURE

实验过程

The compound of step 1 (254 mg, 507 μmol) and 2,6-dimethylphenol were reacted analogously as described in example 1, step 6. 340 mg of crude title compound were obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-05bb114a324d47be8f5b6eae954ea584
来源数据集: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08580813B2
来源说明: uspto-grants-2013_11

反应 SMILES

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:20]3=[N:21][CH:22]=[CH:23][CH:24]=[C:19]3[N:18]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:17]=2Cl)=[O:15])[CH2:10][CH:9]1[CH2:32][C:33]([O:35][CH3:36])=[O:34])=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:37][C:38]1[CH:43]=[CH:42][CH:41]=[C:40]([CH3:44])[C:39]=1[OH:45]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:20]3=[N:21][CH:22]=[CH:23][CH:24]=[C:19]3[N:18]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:17]=2[O:45][C:39]2[C:40]([CH3:44])=[CH:41][CH:42]=[CH:43][C:38]=2[CH3:37])=[O:15])[CH2:10][CH:9]1[CH2:32][C:33]([O:35][CH3:36])=[O:34])=[O:7])([CH3:4])([CH3:3])[CH3:2]