Chloride → HCID 68754990, compound

Participants

Reaction Steps

A reactor is charged with 1 g (6.06 mmol) of methyl 3-amino-6-methylbenzoate and 1.2 g (11.9 mmol) of triethylamine in 25 ml of dichloromethane. 1.145 g (6.05 mmol) of 4-chloromethylbenzoyle chloride is then added and the mixture is stirred at room temperature for 2 hours. The reacting medium is then washed with 10 ml of a saturated NaHCO3 solution, 10 ml of water and 10 ml of a saturated NaCl solution. The organic phase is dried, evaporated and the obtained residue is triturated in ethylic ether and then in pentane to give a white solid (1.2 g, 66%).

Provenance & Evidence