HCID 68760065, compound → HCID 86660458, compound
Reaction equation
CN1CCN(CC2C=CC(C(NC3C=CC(C)=C(C=3)C(OC)=O)=O)=CC=2)CC1.[F:29][C:30]([F:58])([F:57])[C:31]1[CH:32]=[C:33]([CH:48]=[C:49]([N:51]2[CH:55]=[C:54]([CH3:56])[N:53]=[CH:52]2)[CH:50]=1)[C:34]([NH:36][C:37]1[CH:38]=[CH:39][C:40]([CH3:47])=[C:41]([CH:46]=1)[C:42](OC)=[O:43])=[O:35]>>[F:58][C:30]([F:29])([F:57])[C:31]1[CH:32]=[C:33]([CH:48]=[C:49]([N:51]2[CH:55]=[C:54]([CH3:56])[N:53]=[CH:52]2)[CH:50]=1)[C:34]([NH:36][C:37]1[CH:38]=[CH:39][C:40]([CH3:47])=[C:41]([CH:42]=[O:43])[CH:46]=1)=[O:35]Participants
3
Procedure
The compound is obtained by using the procedures of examples 83 (steps 1 and 2) replacing the methyl 5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)-2-methylbenzoate with the methyl 5-(3-(trifluoromethyl)-5-(4-methyl-1H-imidazol-1-yl)benzamido)-2-methylbenzoate.
Workup
- customThe compound is obtained
Sources & evidence
- ORD record
- ord-49d71fd6dbb44a0c833dc0166afc3dcd
- Source dataset
- uspto-grants-2013_11
- Patent number
- US08580815B2
Reaction notes
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