2-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acid → HCID 49834423, compound

HRID 2040064Notes

Reaction equation

HRID 2040064 reaction equation
[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3].[CH3:17][C:18]1[O:19][C:20]([C:26]2[CH:31]=[CH:30][CH:29]=[C:28]([C:32]([F:35])([F:34])[F:33])[CH:27]=2)=[C:21]([C:23](O)=[O:24])[N:22]=1>>[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:23]([C:21]3[N:22]=[C:18]([CH3:17])[O:19][C:20]=3[C:26]3[CH:31]=[CH:30][CH:29]=[C:28]([C:32]([F:35])([F:33])[F:34])[CH:27]=3)=[O:24])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3]

Participants

3

Reactant 2

HCID 669291162-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acidHCID 671276722-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 49834423HCID 49834423, compound

Procedure

Following general procedure Z2, starting from 2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 2-methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-4fc3debc58cf4de691b3aa993e2f744a
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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