Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2040071Generated: October 31, 2026

2-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine → 5-(3-Fluoro-5-methyl-phenyl)-2-methyl-oxazole-4-carboxylic acid{2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

https://huagongshe.com/reaction/2040071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67127672—
ReactantHCID 67127696HCID 67127696—
Product5-(3-Fluoro-5-methyl-phenyl)-2-methyl-oxazole-4-carboxylic acid{2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amideHCID 49834602—

Reaction Steps

Following general procedure Z2, starting from 2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-fluoro-5-methyl-phenyl)-2-methyl-oxazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08580831B2
Source datasetuspto-grants-2013_11
ORD IDord-53b926477d0a4269a88fed73952a4e38
Source noteuspto-grants-2013_11