5-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid → HCID 49834604, compound

HRID 2040073Notes

Reaction equation

HRID 2040073 reaction equation
[F:1][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:4])[CH3:3].[Cl:17][C:18]1[CH:19]=[C:20]([C:24]2[O:28][C:27]([CH3:29])=[N:26][C:25]=2[C:30](O)=[O:31])[CH:21]=[CH:22][CH:23]=1>>[F:4][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:30]([C:25]3[N:26]=[C:27]([CH3:29])[O:28][C:24]=3[C:20]3[CH:21]=[CH:22][CH:23]=[C:18]([Cl:17])[CH:19]=3)=[O:31])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:1])[CH3:3]

Participants

3

Reactant 2

HCID 534307265-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acidHCID 67127834HCID 67127834, compound

Product 1

HCID 49834604HCID 49834604, compound

Procedure

Following general procedure Z2, starting from 2-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-133b011137f84076989837493f946a20
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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