5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acid → HCID 49834777, compound

HRID 2040077Notes

Reaction equation

HRID 2040077 reaction equation
[F:1][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:4])[CH3:3].[CH3:17][N:18]([CH3:33])[C:19]1[CH:20]=[C:21]([C:25]2[O:29][CH:28]=[N:27][C:26]=2[C:30](O)=[O:31])[CH:22]=[CH:23][CH:24]=1>>[F:4][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:30]([C:26]3[N:27]=[CH:28][O:29][C:25]=3[C:21]3[CH:22]=[CH:23][CH:24]=[C:19]([N:18]([CH3:33])[CH3:17])[CH:20]=3)=[O:31])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:1])[CH3:3]

Participants

3

Reactant 2

HCID 532113435-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acidHCID 67127834HCID 67127834, compound

Product 1

HCID 49834777HCID 49834777, compound

Procedure

Following general procedure Z2, starting from 2-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-dimethylamino-phenyl)-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-e25dc99539e048c99b154a00a901f3ad
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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