5-(4-Fluorophenyl)-1,3-oxazole-4-carboxylic acid → HCID 49834084, compound

HRID 2040083Notes

Reaction equation

HRID 2040083 reaction equation
[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3].[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[O:28][CH:27]=[N:26][C:25]=2[C:29](O)=[O:30])=[CH:20][CH:19]=1>>[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:29]([C:25]3[N:26]=[CH:27][O:28][C:24]=3[C:21]3[CH:22]=[CH:23][C:18]([F:17])=[CH:19][CH:20]=3)=[O:30])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3]

Participants

3

Reactant 2

HCID 529838705-(4-Fluorophenyl)-1,3-oxazole-4-carboxylic acidHCID 671276722-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 49834084HCID 49834084, compound

Procedure

Following general procedure Z2, starting from 2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(4-fluoro-phenyl)-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-b88fbf43af394a26b52fc733bcf1970b
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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