5-Phenyl-1,3-oxazole-4-carboxylic acid → HCID 49834262, compound

HRID 2040086Notes

Reaction equation

HRID 2040086 reaction equation
[F:1][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:4])[CH3:3].[C:17]1([C:23]2[O:27][CH:26]=[N:25][C:24]=2[C:28](O)=[O:29])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:4][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:28]([C:24]3[N:25]=[CH:26][O:27][C:23]=3[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)=[O:29])[CH:13]=[N:12]2)=[CH:7][CH:6]=1)([F:1])[CH3:3]

Participants

3

Reactant 2

HCID 27762995-Phenyl-1,3-oxazole-4-carboxylic acidHCID 67127834HCID 67127834, compound

Product 1

HCID 49834262HCID 49834262, compound

Procedure

Following general procedure Z2, starting from 2-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-phenyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-e9c3b8c4fe524d9d8d7a422dc207108c
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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