2-Ethyl-5-phenyl-oxazole-4-carboxylic acid → HCID 49834264, compound

HRID 2040088Notes

Reaction equation

HRID 2040088 reaction equation
[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH2:16])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3].[CH2:17]([C:19]1[O:20][C:21]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[C:22]([C:24](O)=[O:25])[N:23]=1)[CH3:18]>>[F:1][C:2]([C:5]1[N:6]=[C:7]([CH2:10][N:11]2[N:15]=[C:14]([NH:16][C:24]([C:22]3[N:23]=[C:19]([CH2:17][CH3:18])[O:20][C:21]=3[C:27]3[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=3)=[O:25])[CH:13]=[N:12]2)[S:8][CH:9]=1)([F:4])[CH3:3]

Participants

3

Procedure

Following general procedure Z2, starting from 2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 2-ethyl-5-phenyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-b6bcbca58a4e4cfb9b999f6be46338e9
Source dataset
uspto-grants-2013_11
Patent number
US08580831B2

Reaction notes

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