Pivaloyl chloride → HCID 59676036, compound

HRID 2040460Notes

Reaction equation

HRID 2040460 reaction equation
[CH3:1][N:2]1[C:14]2[C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[S:11][CH2:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[C:6]([OH:19])[CH:7]=2.[C:20](Cl)([C:22]([CH3:25])([CH3:24])[CH3:23])=[O:21]>>[CH3:1][N:2]1[C:14]2[C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[S:11][CH2:10][C:9]=2[C:8]2[C:3]1=[CH:4][CH:5]=[C:6]([O:19][C:20](=[O:21])[C:22]([CH3:25])([CH3:24])[CH3:23])[CH:7]=2

Participants

3

Reactant 2

HCID 62493Pivaloyl chlorideHCID 44411867HCID 44411867, compound

Product 1

HCID 59676036HCID 59676036, compound

Procedure

Following the procedure in Example 80, using 11-methyl-6,11-dihydro-5-thia-11-aza-benzo[a]fluoren-8-ol (105 mg, 0.393 mmol) and PivCl (71 mg, 0.59 mmol) as the starting material, the title compound was prepared as a white solid.

Sources & evidence

ORD record
ord-a201ffe6fe5a4e02851e1285f3c9cc02
Source dataset
uspto-grants-2013_11
Patent number
US08580840B2

Reaction notes

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