Citric Acid → Aspirin potassium

HRID 2040496Notes

Reaction equation

HRID 2040496 reaction equation
[CH3:1][C:2]([O:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:10]=1[C:11]([OH:13])=[O:12])=[O:3].C(=O)(O)[O-].[K+:18].C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O>[C:2]([O:4][C:5]1[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=1)[C:11]([O-:13])=[O:12])(=[O:3])[CH3:1].[K+:18]

Participants

5

Reactant 3

HCID 311Citric AcidHCID 2244Aspirin2×HCID 516893Potassium Bicarbonate

Product 1

HCID 23676700Aspirin potassium

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

The ˜2 gram dose form soluble aspirin composition of EXAMPLE 1 dissolves in water in less than 30 seconds to constitute a ready to drink dose, when added to 2 ounces of cold water. Upon combination of the dry solids composition with water, a chemical reaction takes place that reacts the aspirin, potassium bicarbonate and citric acid, to yield potassium acetylsalicylate. The potassium acetylsalicylate immediately dissolves in water, leaving no undissolved residue.

Sources & evidence

ORD record
ord-83509f826d8843c0bd21324055b82979
Source dataset
uspto-grants-2013_11
Patent number
US08580853B2

Reaction notes

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