HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86656463, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(tert-Butyloxycarbonyl)glycine N-hydroxysuccinimide ester | HCID 76926 | — |
| Reactant | HCID 58388311 | HCID 58388311 | — |
| Reactant | HCID 86656464 | HCID 86656464 | — |
| Product | HCID 86656463 | HCID 86656463 | — |
Reaction Steps
(S)-2-(2-aminoacetamido)-4-(methylthio)butane-1-sulfonic acid hydrochloride was synthesized by coupling a 2,5-dioxopyrrolidin-1-yl 2-(tert-butoxycarbonylamino)acetate to sodium (S)-2-amino-4-(methylthio)butane-1-sulfonate in the presence of mild base. The resulting (S)-2-(2-(tert-butoxycarbonylamino)acetamido)-4-(methylthio)butane-1-sulfonic acid was deprotected in the presence of 6M HCl(aq.) to provide the desired product. (M+H)+=256.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580859B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-42998349f8a14f5fabed0bbdea6e8419 |
| Source note | uspto-grants-2013_11 |