HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Cyano-5-(trifluoromethoxy)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Cyano-5-(trifluoromethoxy)benzoic acid | HCID 21942532 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 3-Cyano-5-(trifluoromethoxy)benzoyl chloride | HCID 86646992 | — |
Reaction Steps
Oxalyl chloride (2.0 M in DCM, 0.636 mL, 1.272 mmol) was added to neat 3-cyano-5-(trifluoromethoxy)benzoic acid (98 mg, 0.424 mmol) and one drop of DMF was added. The reaction mixture was stirred at room temperature for 30 min and then concentrated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580841B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-3aedfb3f6d974af794f663fc056441b3 |
| Source note | uspto-grants-2013_11 |