HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Methyl-6-(2-methyl-propyl)-isonicotinic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Methyl-6-(2-methyl-propyl)-isonicotinic acid ethyl ester | HCID 57437201 | — |
| Product | 2-Methyl-6-(2-methyl-propyl)-isonicotinic acid hydrochloride | HCID 67026961 | — |
Reaction Steps
A solution of 2-methyl-6-(2-methyl-propyl)-isonicotinic acid ethyl ester (9.78 g, 45.1 mmol) in 6 N aq. HCl (20 mL) is stirred at 95° C. for 20 h before the solvent is evaporated. The residue is dried under HV to give 2-methyl-6-(2-methyl-propyl)-isonicotinic acid hydrochloride (9.56 g) as a colourless solid, LC-MS: tR=0.52 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08580824B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-0f3e6858c22a454582526d2a03276e8a |
| Source note | uspto-grants-2013_11 |